Published Studies

The members of the birmingham bowel clinic have been invited to give lectures at national and international meetings and all are actively engaged in scientific research. The members regularly present their research findings at scientific meetings and publish their research in scientific journals.

To find out more about more about the research activities for each Birmingham Bowel Clinic consultant, please click on their name in the drop down menu.

Published Studies - Tariq Ismail

Men's experience of erectile dysfunction after treatment for colorectal cancer: qualitative interview study.
Dowswell G, Ismail T, Greenfield S, Clifford S, Hancock B, Wilson S.
BMJ. 2011 Oct 18;343:d5824. doi: 10.1136/bmj.d5824.
PMID: 22010127

The effect of seeking consent on the representatives of patient cohorts: iron deficiency anaemia and colorectal cancer.
Damery S, Ryan R, McManus RJ, Warmington S, Draper H, Wilson S; Improving Colorectal Outcomes (ICOS) Group.
Colorectal Dis. 2011 Nov;13(11):e366-73. doi: 10.1111/j.1463-1318.2011.02724.x.
PMID: 21831101

Assessment of novel combinations of biomarkers for the detection of colorectal cancer.
Shimwell NJ, Wei W, Wilson S, Wakelam MJ, Ismail T, Iqbal T, Johnson PJ, Martin A, Ward DG.
Cancer Biomark. 2010;7(3):123-32.
PMID: 21263188

Iron deficiency anaemia and delayed diagnosis of colorectal cancer: a retrospective cohort study
Damery S, Ryan R, Wilson S, Ismail T, Hobbs R; Improving Colorectal Outcomes Group.
Colorectal Dis. 2011 Apr;13(4):e53-60. doi: 10.1111/j.1463-1318.2010.02488.x.
PMID: 21054747

Sutures v staples. What about the NICE guidelines?
Pinkney TD, Pandey S, Radley S, Ismail T.
BMJ. 2010 May 18;340:c2631. doi: 10.1136/bmj.c2631.
PMID: 20483935

The prevalence of erectile dysfunction in post-treatment colorectal cancer patients and their interests in seeking treatment: a cross-sectional survey in the west-midlands
Ellis R, Smith A, Wilson S, Warmington S, Ismail T.
J Sex Med. 2010 Apr;7(4 Pt 1):1488-96. Epub 2009 Aug 17.
PMID: 19694923

Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme
Wilson S, Taskila T, Ismail T, Stocken DD, Martin A, Redman V, Wakelam M, Perry I, Hobbs R.
BMC Cancer. 2009 Jan 28;9:36.
PMID: 19175925

Proteomic profiling of urine for the detection of colon cancer

Ward DG, Nyangoma S, Joy H, Hamilton E, Wei W, Tselepis C, Steven N, Wakelam MJ, Johnson PJ, Ismail T, Martin A.
Proteome Sci. 2008 Jun 16;6:19.
PMID: 18558005

Expression and function of T cell homing molecules in Hodgkin's lymphoma

Machado L, Jarrett R, Morgan S, Murray P, Hunter B, Hamilton E, Crocker J, Thomas W, Steven N, Ismail T, Chapman A, Adams DH, Lee SP.
Cancer Immunol Immunother. 2009 Jan;58(1):85-94. Epub 2008 May 17.
PMID: 18488221

Increased hepcidin expression in colorectal carcinogenesis

Ward DG, Roberts K, Brookes MJ, Joy H, Martin A, Ismail T, Spychal R, Iqbal T, Tselepis C.
World J Gastroenterol. 2008 Mar 7;14(9):1339-45.
PMID: 18322945

Bacteriophage biopanning in human tumour biopsies to identify cancer-specific targeting ligands

Maruta F, Akita N, Nakayama J, Miyagawa S, Ismail T, Rowlands DC, Kerr DJ, Fisher KD, Seymour LW, Parker AL.
J Drug Target. 2007 May;15(4):311-9.
PMID: 17487700

Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population

Wilson S, Wakelam MJ, Hobbs RF, Ryan AV, Dunn JA, Redman VD, Patrick F, Colbourne L, Martin A, Ismail T.
BMC Cancer. 2006 Oct 31;6:258.
PMID: 17076885

A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer

Ryan AV, Wilson S, Wakelam MJ, Warmington SA, Dunn JA, Hobbs RF, Martin A, Ismail T.
BMC Cancer. 2006 Oct 23;6:251.
PMID: 17059590

Identification of FGF receptor-binding peptides for cancer gene therapy

Maruta F, Parker AL, Fisher KD, Hallissey MT, Ismail T, Rowlands DC, Chandler LA, Kerr DJ, Seymour LW.
Cancer Gene Ther. 2002 Jun;9(6):543-52.
PMID: 12032665

W A Jurewicz, B K Gunson, T Ismail, L Angrisani and P McMaster
Cyclosporin and anti-tuberculous therapy.
The Lancet 1985; I: 1343. (letter)

R M Kirby, T Ismail, M C Crowson and R M Baddeley
Gastric banding in the treatment of morbid obesity.
British Journal of Surgery 1989; 76: 490-492

T Ismail, B Gunson, J Buckels and P McMaster
Managing Biliary Atresia.
British Medical Journal 1989; 299: 257-258

P McMaster and T Ismail
Pancreatic Transplantation.
Current Opinions in Gastroenterology 1989; 5: 711-715

T Ismail, R M Kirby, M C Crowson and R M Baddeley
Vertical silastic ring gastroplasty: a six year experience.
British Journal of Surgery 1990; 77: 80-82

J Howl, T Ismail, A Strain and M Wheatley
Does vasopressin receptor have a significant role in the hormonal regulation of human liver function?
Biochemical Society Transactions 1990; 18: 399-400

T Ismail, L Angrisani, B K Gunson, S Hubscher, J Buckels, J Neuberger, E Elias and P McMaster
Primary Hepatic Malignancy: the role of liver transplantation.
British Journal of Surgery 1990; 77: 983-987

T Ismail and P McMaster
Pancreas Transplantation.
Current Opinions in Gastroenterology 1990; 6: 798-802

R Ayres, T Ismail, J Buckels, J Neuberger, E Elias and P McMaster
Long-term renal function in liver transplantation.
Transplantation Proceedings 1991; XXIII (1): 1469-1470

T Ismail, L Angrisani, S Hubscher and P McMaster
Hepatocellular carcinoma complicating primary sclerosing cholangitis.
British Journal of Surgery 1991; 78: 360-361

T Ismail, L Angrisani, J E Powell, S Hubscher, J Buckels, J Neuberger,E Elias and P McMaster
Primary Sclerosing Cholangitis: surgical options, prognostic variables and outcome.
British Journal of Surgery 1991; 78: 564-567

A J Strain, T Ismail, H Tsubouchi, T Hishida, N Kitamura, Y Daikuhara and P McMaster
Native and recombinant human Hepatocyte Growth Factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes.
Journal of Clinical Investigation 1991; 87: 1853-1857

J Howl, T Ismail, A J Strain, D Anderson and M Wheatley
Characterisation of the human vasopressin receptor.
The Biochemical Journal 1991; 276: 189-195

T Ismail, J Howl, M Wheatley, J Neuberger, P McMaster and A J Strain
Growth of normal human hepatocytes in primary culture: effect of hormones and growth factors on DNA synthesis.
Hepatology 1991; 14: 1076-1082

Angrisani L, Ismail T, Lorenzo M, McMaster P
Il trapianto di fegato nella malattia neoplastica
Chirurgia Generale - General Surgery 1992 X111 (4) 259-264

Mirza DF, Ismail T, Ferraz-Neto BH, McMaster P
Live-Organ Donation and Transplantation
Clinical Transplantation 1994. 350-1

M Lorenzo, Angrisani, R Ventrigla, T Ismail, B Tesauro
Techniques of total hepatectomy in the rat.
Microsurgery 1995; 16(7): 493-5

D F Mirza, T Ismail, B H Ferraz Neto, P McMaster
Live Organ Donation and Transplantation
Clinical Transplants 1994; 350-1

T Ismail, M T Hallissey and J W L Fielding
Pathological and oncological prognostic factors in gastrointestinal cancer.
World Journal of Surgery 1995; 19(2): 178-183

T Ismail, R Ayres, P Kiff, J Neuberger and P McMaster
Enisoprost in liver transplantation.
Transplantation 1995; 59(9): 1298-301
Liver Transplantation (Chapter)

T Ismail, B. Ferraz-Neto and P McMaster
In Rob & Smith’s Operative Surgery (5th Edition, 1995)

McMaster P, Mirza DF, Ismail T, Vennarecci G, Patapis P, Mayer AD
Therapeutic Drug Monitoring of Tacrolimus in Clinical Transplantation
Thes Drug Monit. 1995; (6): 602-5

Lorenzo M, Angrisani L, Ventriglia R, Ismail T, Tesauro B
Technique of total hepatectomy in the rat.
Microsurgery. 1995;16(7):493-5

Vennarecci G, Gunson BK, Ismail T, Hubscher SG, Kelly DA, McMaster P, Elias E
Transplantation for End Stage Liver Disease Related to Alpha 1 Antitrypsin
Transplantation 1996. 27; 61(10): 1488-95

Mirza D F, Gunson B K, Ferraz-Neto B H, Ismail T, Mayer A D, Buckels J A, McMaster P
“Evaluation of the UK super-urgent liver transplant scheme”.
Transplantation Proceedings 1996; 28 (1): 244-245

Ferraz-Neto B H, Mirza D F, Funson B K, Ismail T, Mayer A D, Buckels J A, McMaster P
“Bile duct splintage in liver transplantation: is it necessary?”
Transplant International 1996; 9 Suppl 1: S185-S187

Vennarecci G, Ismail T, Gunson B, McMaster P. “L’angiosarcoma primitivo del fegato. (Primary angiosarcoma of the liver)”
Minerva Chirurgica 1997; 52(10): 1141-1146 (Italian)

Lorenzo M, Angrisani L, Ismail T, Prisco B D, Bassi U A, Roina G, Ventrigla R, Santuro T
Hepatocyte Transplantation in Anhepatic Rat - Preliminary Results.
Gastroenterology International 1997; 10(3) 879-880

Wong L S, Rusby J, Bassi U A, Rowlands D, Ismail T
Stromal Tumour of the Small Bowel
Journal of The Royal Society of Medicine 2000; 3: 145-6

Wong L, Rusby J, Bassi A, Ismail T
Left Sided Gallbladder: a Diagnostic and Surgical Challenge
ANZ J Surg. 2001; 71(9): 557-8

Lipinski KS, Djeha AH, Ismail T, Mountain A, Young LS, Wrighton CJ
High-level, B-Catenin/TCF-dependent Transgene Expression in Secondary Colorectal Cancer Tissue.
Molecular Therapy 2001; 4(4): 365-371

Hurst NG, Wakelam MJ, Ismail T
Colorectal Neoplasia - Serological Risk Stratification of Symptomatic Patients
Journal of The Royal College of Surgeons of Edinburgh 2001; Page No: 59

Hartley A, Giridharan S, Gray L, Billingham L, Ismail T, Geh J I
Acute Toxicity Following Short Course Preoperative Radiotherapy: a Retrospective Study
British Journal of Surgery 2002; 89: 889-895

Invited Lectures - Simon Radley

Bile acids in colorectal carcinogenesis
Gastroenterology: current issues in inflammatory bowel disease and colorectal cancer.
British Council Course, Birmingham, March 1993.

Hospital at home for minor anal surgery
Association of Coloproctology, Edinburgh, June 1997.

Rectal prolapse.
M54 Coloproctology Course, Wolverhampton, 1998-2009

Basic surgical skills,
Russells Hall Hospital, Dudley,1998-2008

The ileo-anal pouch for Crohn's disease.
Medical/ Surgical G.I. Masterclass- "The Colon", Royal Free Hospital, London, February 1999.

From end-to-end suture to the artificial sphincter where next?
"Lets put the old Millennium behind us!".
Swansea, September 1999

Intra partum anal sphincter injuries should be repaired by a surgical coloproctologist.
Gastrointestinal dysfunction in pregnancy. Royal College of Obstetricians & Gynaecologists,London, June 2000

Local excision of rectal cancer
1st International course on advances in colorectal surgery, Santander Spain, January 2001

Alternative surgical treatments for faecal incontinence
1st International course on advances in colorectal surgery,Santander Spain, January 2001

Constipation.
Colorectal SPR Training Day, Woverhampton 2001

Surgical management of post-partum incontinence
Incontinence in Women 42nd RCOG Study Group, Royal College of obstetricians & Gynaecologists, London, October 2001

Therapeutic options for early rectal carcinoma
2nd International course on advances in colorectal surgery, Santander Spain, January 2002

The fast track colorectal clinic
2nd International course on advances in colorectal surgery, Santander Spain, January 2002

Follow up of colorectal cancer
Liver Metastases From Colorectal Cancer, Birmingham, May 2002

Management of a septic patient with diverticulitis. Arguments against primary anastomosis.
Association of Surgeons, Dublin, May 2002

Surgical management of faecal incontinence
Incontinence in Women & Perineal Trauma, Royal College of Obstetricians & Gynaecologists, London, June 2002.

Project to define and pilot clinical indicators for urinary and faecal incontinence.
Faecal incontinence workshop. Royal College of Physicians, Clinical Effectiveness Unit, London June 2002

Intestinal fistulae.
Colorectal SPR Training Day, Woverhampton 2002

Surgical options in acute diverticulitis
M62 course, Huddersfield, March 2003

Recurrent colorectal cancer.
Colorectal SPR Training Day, Woverhampton 2003

Anal cancer.
Oncology Trainees,Birmingham 2004

Surgery for inflammatory bowel disease.
Gastroenterology Trainees, Birmingham 2004

Trauma to the colon, rectum & anus.
Colorectal SPR Training Day, Woverhampton 2004

Constipation and obstructed defeacation.
MASTIG, Birmingham, June 2004

A colorectal surgeons view of obstetric anal sphincter injuries.
SPROGS, Birmingham, June 2004

Endoanal & endorectal ultrasonography,
Association of Coloproctology, Birmingham, June 2004

Co-chairman.
West Midlands IBD Forum, Birmingham November 2004

Surgery for cancer and diverticular disease.
Gastroenterology Trainees, Birmingham January 2005.

Techniques of endosonography, normal anal and rectal anatomy.
Midlands Ano-Rectal UltraSonography Course, Birmingham, May, 2005-2010.

Local treatments for cancer,
Colorectal SPR Training Day, Woverhampton 2005.

Laparoscopic colorectal surgery.
Gastroenterology Trainees, Birmingham January 2006.

How to manage severe acute colitis not responding to intensive medical therapy.
Association of Coloproctology Teaching Day for SPR’s. Birmingham, May 2006.

Colorectal SPR Training Day, Woverhampton 2006.

Evaluation of anorectal function: imaging, physiology, electromyography.
BAUS. Female Pelvic Organ Prolapse. A Multidisciplinary Update. Birmingham, April 2007.

Development in the diagnosis and treatment of colorectal cancer: Management of the elective patient.
British Institute of Radiology, Presidents Conference, Hoar Cross Hall, May 2007.

Surgical management of anal cancer.
Clinical SpR Training Day on Anal Cancer. Birmingham, July 2007

Complicated surgical Crohn’s disease.
Updates for trainees in gastroenterology and GI surgery. Birmingham, September 2007.

Management of rectoceles: a colorectal viewpoint.
British Society of Urogynaecology, London, June 2008.

Surgical management of anal incontinence.
Childbirth and Pelvic Floor Trauma, Joint RCOG/BSUG Meeting, London, October 2008

Laparoscopic ileoanal pouch surgery.
Moynihan Club Meeting. Birmingham, October 2008.

Surgical management of anal cancer.
Clinical SpR Training Day on Anal Cancer. Birmingham, 2010.

Nottingham

South West Laparoscopic Surgical Group

Midlands Laparoscopic surgical Group

Beyond Laxatives: Optimising the management of chronic constipation

Chairman

Birmingham, September 2010

Pouch procedure
West Midlands Laparoscopic Colorectal Group, Birmingham, November 2010